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REVIEW Methadone: applied pharmacology and use as adjunctive …
WebDosing. Analgesia: (oral, iv) Peak effect 2 hr after oral: Peak effect 15-20 min after iv administration. Administered every 8 hr. Convert from 24 hr oral morphine requirements, … WebMethadone is a synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and … Web14 apr. 2004 · Methadone: applied pharmacology and use as adjunctive treatment in chronic pain R Brown, C Kraus, M Fleming, S Reddy..... Postgrad Med J … mp3 won\u0027t play in itunes