Ctgf migration
WebNov 4, 2016 · CTGF is a matricellular, multifunctional protein that can influence the activity of multiple major signaling pathways, affecting cell adhesion, migration, proliferation, and differentiation. CTGF expression increases after central nervous system (CNS) trauma in rodents, but its function after spinal cord injury has not been elucidated ( 7 – 9 ). WebMar 3, 2004 · Connective tissue growth factor (CTGF, also known as CCN2) is a member of the CCN family, which includes CTGF, cysteine-rich 61 (Cyr61, ... (20– 22); endothelial cell proliferation and migration (23, 24); and regulation of apoptosis in human breast cancer cells and aortic smooth muscle cells (25, 26).
Ctgf migration
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WebDec 12, 2024 · Angiogenesis is the main basis of the proliferative phase of wound healing, cell proliferation, migration, and differentiation. The integrity of the endothelial cell structure plays a very important role in maintaining normal blood circulation in the body. ... Connective tissue growth factor (CTGF) is a matricellular protein from the … WebIn the former study, we discovered that the expression of adiponectin was obviously decreased in keloid tissues compared with those in normal controls, furthermore, adiponectin inhibited CTGF-mediated KFs proliferation, migration and the over-accumulation of ECM. 13 But the correlation between adiponectin and inflammatory …
WebAug 6, 2024 · Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis. ... In addition to fibrosis, CTGF has multiple functions, including cell adhesion and migration. CTGF expression is upregulated in ... WebConnective tissue growth factor (CTGF), a cystine-knot protein of the CCN family, interacts with a variety of biological response modifiers and participates in several biological processes such as cell proliferation, migration, differentiation, and development of bone, cartilage, and angiogenesis. TGF-b upregulates CTGF expression in ...
WebApr 12, 2024 · Corning 3422 inserts were used to evaluate the cell migration capacity. HLF and Hep3B cells were transfected with siUSP1 or siControl. ... The expression of CTGF, the most classical Hippo target ... WebCCN2 promotes fibroblast proliferation, matrix production, and granulation tissue formation, as well as cell adhesion and migration. Experiments using recombinant CTGF and neutralizing antibodies targeting CTGF have suggested that CTGF mediates at least some of the effects of TGF-β on fibroblast proliferation, adhesion, and ECM production ...
WebConnective tissue growth factor (CTGF) is a signaling molecule with several roles in tissue repair and regeneration including promoting cell adhesion, cell migration, cell proliferation and angiogenesis. ... Results of the in vitro scratch assay shows that the membranes containing CTGF promoted cell migration and supported fast in vitro wound ...
WebJul 1, 2024 · Intriguingly, the effect of CTGF on cell migration can either be positive or negative in a cell-type-specific manner [23,24]. The differential actions of CTGF may be … u of u shoreline ridgeWebJul 18, 2024 · This analysis also revealed several other up-regulated genes such as A2m and Nfkbiz as members of Il-6, Cxcl1, Ctgf, and Tgfb2 interactome . Future experimental studies may validate the potential role up-regulation of Il-6, Cxcl1, Ctgf, and Tgfb2 may have in promoting cancer cell migration, invasion, and cancer-induced bone metabolism. u of u station parkWebFeb 6, 2024 · The migration assays showed that GFs with CM from CAFs strongly enhanced GIST-T1 cell migration compared to GF only, while the effect was markedly decreased by anti-TGF-β1 blocking antibody (Fig ... recovery eaasWebJun 3, 2013 · To examine the effect of CTGF on cell migration, stably shRNA-CTGF-expressing 1024 and 1047 6–10B NPC cells were cultured on transwell apparatus. ... Li … recovery e21WebAs shown in Fig. 5, the number of Panc-1 cells that invaded through the matrigel chamber was signi fi cantly less in the group transfected with MUC1 siRNA than that observed in control groups (P b ... recovery easierWebJun 1, 2006 · Connective tissue growth factor (CTGF) is a member of the CCN [CYR61 (cysteine-rich 61) / CTGF / NOV (nephroblastoma overexpressed)] family of secreted proteins, which are characterized as cysteine-rich matricellular proteins that each contain four modular domains displaying homology to insulin-like growth factor–binding proteins … u of u south jordan labWebOct 29, 2024 · Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved in different biological processes, such … u of u south main clinic