Web029926 B6.FVB-Tg(Cspg4-cre)1Rkl/J NG2-cre transgenic mice express Cre recombinase in Cspg4 expressing pericytes. These mice may be useful for Cre-lox studies related to … WebFeb 16, 2024 · Because the Rosa26 Cre-ER-T2/+ allele is expressed in tumor cells and non-tumor cells, the results using the Rosa26 Cre-ER-T2/+ mice may be due to a non-sarcoma cell effect of NG2/CSPG4 regulating the niche to alter tumor behavior. Therefore, we generated mice in which Ng2/Cspg4 would be deleted only in the tumor cells. To …
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WebMar 7, 2024 · Results: Fluorescent imaging of Cspg4-Cre;tdTomato vessels demonstrated dim PLVs and strong reporter gene expression in the adjacent superficial saphenous … WebJan 10, 2024 · Overexpression of the chondroitin sulfate proteoglycan 4 (CSPG4) has been associated with the pathology of multiple types of such as melanoma, breast cancer, squamous cell carcinoma, mesothelioma, neuroblastoma, adult and pediatric sarcomas, and some hematological cancers. CSPG4 has been reported to exhibit a role in the growth … easy crumbed fish recipe
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WebAug 19, 2024 · The specificity and pattern of cre activation varied significantly across the three lines, under either the PDGFRβ or NG2 promoter (Pdgfrβ-CreRha, Pdgfrβ-CreCsln, and Cspg4-Cre). In particular, a mouse line with Cre under the NG2 promoter resulted in sparse TdTomato labeling of mural cells, allowing for an unambiguous characterization of ... WebMar 21, 2024 · CSPG4 (Chondroitin Sulfate Proteoglycan 4) is a Protein Coding gene. Diseases associated with CSPG4 include Melanoma and Demyelinating Disease.Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and Glycosaminoglycan metabolism.Gene Ontology (GO) annotations related to this gene … WebOct 10, 2024 · Finally, the Cspg4-Cre/Esr1*:Dsp F/F mice did not show evidence of cardiac dysfunction, which would be expected on deletion of Dsp in cardiac myocytes, as reported previously. 19 Consequently, the data indicate that cardiac arrhythmias and conduction defects in the Cspg4-Cre/Esr1*:Dsp F/F mice are independent of cardiac myocytes and … curafair volkshilfe